About DSD

Differences in sex development (DSD) are variations in the development of sexual organs and other sex-related structures in relation to sex chromosomes, hormones, and other developmental factors. (Also see alternate terms in DSD.)

DSD conditions may be classified into three major groups:

  • 46,XY DSD
  • 46,XX DSD
  • Sex chromosome DSD

Some common and rare DSD conditions are listed below:

For more terms related to DSD, please see the Glossary.

Learn more about DSD on the St. Louis Children’s Hospital page.